evidence corpus · 82 cards
Every claim, graded.
GRADE-style evidence cards backing the scoring engine. Each card captures the consensus position on one health claim, grouped by medical domain and color-coded by evidence level (H5 strongest → H1 weakest).
82cards
44domains
217posts audited
29accounts
Evidence level distribution
Nutrition
10 cards
A sustained calorie deficit is the primary mechanism of weight/fat loss (regardless of macronutrient ratios)
6·3
The vast majority of human health issues are solved by eating single-ingredient foods and avoiding UPF
3·3
Red meat intake supports cognitive function in adults via carnitine, creatine, taurine, B12
1·1
Non-nutritive sweeteners at typical intakes do not cause insulin spikes, blood-sugar issues, or measurable cardiometabolic harm
1·1
Commercial electrolyte hydration drinks (e.g., LMNT, Liquid IV) provide meaningful hydration or health benefit beyond plain water for the general population
1·1
Saturated fat is heart-healthy or harmless
5·4
Common artificial food dyes cause meaningful health harm in humans
1·1
Seed oils (industrial vegetable oils) are toxic and cause chronic disease in humans
3·3
Industrial vegetable / seed oils are uniquely harmful to human health
3·3
Spinach is the worst leafy green to eat because of pesticides and oxalates
1·1
Lipids
6 cards
LDL cholesterol is causal for atherosclerotic cardiovascular disease
29·8
Statins reduce cardiovascular events in primary prevention in moderate-to-high risk adults
6·3
Statins reduce cardiovascular events in secondary prevention
5·4
Lower LDL-C targets (e.g., <70 mg/dL high-risk, <55 mg/dL very-high-risk/post-event) reduce cardiovascular events
4·1
Statins reduce inflammatory markers (hs-CRP) robustly in RCTs
1·1
Higher LDL in older adults is cardioprotective
2·2
Drugs
5 cards
GLP-1 receptor agonists (semaglutide, tirzepatide) deliver large health benefits for people with obesity/T2D
12·9
Carvedilol causes vasodilation via alpha-1 adrenergic receptor blockade in addition to its beta-blocking activity
1·1
Orforglipron (oral GLP-1) produces ~16% body-weight loss in Phase 3 and beats oral semaglutide head-to-head
—
Metoprolol and atenolol are first-line antihypertensive agents for uncomplicated hypertension
3·1
Statins reduce dementia and Alzheimer's disease risk
3·1
Supplements
4 cards
Fish oil / omega-3 supplements reduce cardiovascular events in the general population
2·2
CoQ10 prevents or treats statin-associated muscle symptoms
1·1
Magnesium deficiency is widespread and most adults benefit from supplementation across multiple forms
1·1
Hydrogen-rich water provides therapeutic benefit for PMS or other clinical indications
1·1
Environmental
4 cards
Environmental toxins are a major, under-recognized driver of modern chronic disease (hormones, metabolism, brain)
3·2
Fragranced personal-care products contain endocrine disruptors that meaningfully harm human hormones
2·1
PFAs in synthetic activewear are meaningfully absorbed through skin during exercise and harm health
1·1
Tattoo inks contain heavy metals and bacteria that cause systemic health harm
1·1
Screening
4 cards
A coronary artery calcium (CAC) score of 0 misses early non-calcified plaque in young adults, so CAC is insensitive for early atherosclerosis detection in this population
2·1
Routine inpatient stress testing in low-risk hospitalized patients is low-value care
1·1
Routine liver enzyme (ALT/AST) monitoring is clinically valuable in specific drug and disease contexts
1·1
For selected patients, some cancer / CV screenings should start earlier than current guideline age thresholds
5·3
Exercise
3 cardsSupplements/Longevity
3 cardsExercise/Biomarkers
3 cardsSupplements/Exercise
3 cards
High-dose omega-3 (EPA+DHA, typically ≥2g/day) reduces exercise-induced muscle damage and speeds recovery
1·1
HMB supplementation builds muscle or strength in healthy resistance-training adults
1·1
BCAA supplementation increases muscle protein synthesis or builds muscle beyond what adequate dietary protein provides
1·1