evidence card · saladino_optimal_lab_ranges
Optimal lab ranges are substantially tighter than clinical reference ranges (fasting insulin <5, fasting glucose <80, TSH <2, etc.)
H2
≈ mixed
stakes moderate
1 post scored
·
across 1 account
·
1 sources
Summary
Some tighter targets (e.g., LDL, blood pressure) have RCT backing for high-risk populations. Others (TSH <2, fasting insulin <5) are not established in trials as actionable thresholds. Conflates 'observational association with better health' with 'causal benefit of reaching that threshold'.
Five-score assessment
Scores not yet assigned for this card. (Legacy card; will be populated on next refinement.)
Scope
Population
general adults
Intervention
targeting alternative 'optimal' ranges
Outcome
long-term health outcomes
Not supported for
- broad clinical action based on these tighter thresholds
Evidence sources
Sources
-
guideline AACE/ATA: TSH reference intervals ↗