evidence card · resveratrol_sirtuin_human_benefit
Resveratrol activates sirtuins and produces clinically meaningful longevity benefit in humans
H1
▽ contradicts
stakes moderate
0 posts scored
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across 0 accounts
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2 sources
Summary
Human RCTs of resveratrol for aging outcomes are null or uninterpretable. Original Sirtris story failed translationally; bioavailability is poor; clinical trials did not pan out.
Five-score assessment
Scores not yet assigned for this card. (Legacy card; will be populated on next refinement.)
Scope
Population
humans
Intervention
oral resveratrol
Outcome
healthspan, lifespan, disease prevention
Not supported for
- anti-aging claims
- sirtuin activation as clinical benefit
Evidence sources
Account mentions
No accounts have made claims mapped to this card yet.