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evidence card · hmb_muscle_building_healthy_adults

HMB supplementation builds muscle or strength in healthy resistance-training adults

H2 ▽ contradicts stakes low
1 post scored · across 1 account · 1 sources

Summary

Properly blinded RCTs in healthy trained adults generally show null effects. Earlier positive trials had methodological concerns. HMB may reduce muscle loss in clinical wasting conditions.

Five-score assessment

Scores not yet assigned for this card. (Legacy card; will be populated on next refinement.)

Scope

Population
healthy adults who resistance-train
Intervention
HMB supplementation (typical 3 g/d)
Outcome
lean mass gain, strength
Not supported for
  • muscle-wasting conditions (cachexia, sarcopenia) where modest effects exist

Evidence sources

Account mentions

  • @BioLayne stance: refutes · alignment: aligned · score 100/100 · 2026-04-02 post ↗